MVP
Melatonin
(sleeping aid)
What
exactly
is Melatonin?
"Melatonin
is the all-natural nightcap. It's secreted by the pineal
gland, a pea-size structure at the center of the brain, as
our eyes register the fall of darkness." At night
melatonin is produced to help our bodies regulate our
sleep-wake cycles. The amount of melatonin produced by our
body seems to lessen as we get older. Scientists believe
this may be why young people have less problem sleeping than
older people.
Melatonin is a natural hormone
that’s naturally produced by the pineal gland. As we age,
our body produces less and less, making in more difficult to
fall asleep. MVP Nutrition’s ® Melatonin pharmaceutical
grade with a minimum purity of 99.6%.*
Its
most recognized function is the adjustment of sleeping
patterns (jet-lag). Further, Melatonin has many other
outstanding, yet not broadly known, properties that can
intensify athletic performance. At night Melatonin is
produced to help our bodies regulate our sleep-wake
cycles.
Melatonin
was first identified forty years ago and is now recognized
as one of life's most beneficial molecules.
Physiologists recognize Melatonin as the hormone that
keeps us in sync with the rhythms of the day as well as the
season. Through its effect on other hormones, it helps
determine when people sleep, animals breed, birds migrate
and even when dogs shed their coats.
Melatonin is rapidly gaining recognition as one of
the most effective anti-oxidants available. Interpreting the
true greatness of this dietary supplement may take years,
the most common way of taking Melatonin is simply
before going to sleep - as many people who take it will tell
you they get exactly what they expect!
Though
it was discovered in 1958, it is only recently that melatonin,
a hormone produced by the pineal gland, has been intensively
studied. In 1993 melatonin made its first appearance
as a consumer product hailed for its sleep inducing effect. Melatonin
supplements are being investigated as a potential treatment
to readjust biorhythms and alter sleep cycles in people with
jet lag, the blind, and nightshift workers. It is also being
explored for its potential in the treatment and prevention
of various diseases.
Melatonin
works to maintain the body's circadian rhythms, regulating
such human functions as body temperature, dream sleep, the
sleep/wake cycle, and the secretion of cortisol. The cue for
the release of this hormone begins when the eyes first
register the onset of darkness. The body requires darkness
to produce melatonin. Thus, levels of this hormone are high
at night and low during the day. This chemical is not
produced during daytime naps, as light suppresses its
production.
Melatonin
originates from tryptophan, an essential amino acid which is
obtained through the diet. During the day the body converts
tryptophan into serotonin (a chemical involved in mood).
Serotonin is then converted to melatonin (usually at
night). Large doses of tryptophan increase melatonin levels
and induce sleep.
Unlike
other hormones, melatonin does not need a receptor to
enter a cell membrane and can permeate any part of a cell.
It is absorbed directly into the bloodstream, other tissues
and body fluids. Infants begin producing melatonin about the
fourth day after birth. Prior to birth, melatonin
passes through the placenta to the infant. This chemical is
also present in breast milk.
Melatonin
is found in some plants, mammals, birds, reptiles, and
amoebas, regulating activities such as mating, migration,
and hibernation. Some animals exhibit higher melatonin
levels in fall and winter months when the number of daylight
hours decreases. This same pattern has been noted in women
but not in men. Melatonin levels peak during
childhood and gradually decrease throughout adolescence and
adulthood. Declining levels of this hormone trigger the
onset of puberty in children and menopause in women. Melatonin
levels are lowest in older adults, which may explain the
prevalence of insomnia in this population.
Sufferers
of Seasonal Affective Disorder (SAD) may have high daytime
levels of melatonin and consequently abnormal
circadian rhythms. SAD is a condition marked by depression
associated with the declining level of daytime light during
the winter months. Exposure to light, which can alter the
timing of melatonin secretion, is found to be
therapeutic for this condition.
Melatonin
is being considered as a potential treatment for breast
cancer because of its ability to limit the amount of
estrogen entering cells. High exposure to the hormone
estrogen is believed to be the cause of many types of breast
cancer. In tests on rats, melatonin has been found to
decrease the size of malignant mammary tumors by 50%.1 The
effects of melatonin have also been studied when used
in conjunction with tamoxifen, another anti-estrogen
chemical which is a possible treatment for breast cancer.
These studies indicate tamoxifen is 100 times more effective
against cancer cells that have previously been treated with melatonin.
Research also indicates that patients with high blood levels
of melatonin have greater success with chemotherapy.
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